Barrier-Breaking Extraction Workflows

Fast  |  Efficient  |  Single-tube

"I've used prepGEM Bacteria to prepare DNA for microbiome analyses using both high-throughput sequencing and qPCR methods. The method is quick and easy, minimizes contamination, produces excellent DNA, and represents great value for the money."

Department of Biosciences, University of Swansea, UK

Improved CRISPR Workflows

Efficient extraction for simplified genotyping

"prepGEM Universal is a highly recommended, time-saving, and environment-friendly kit. In fact, it's a must-have in any CRISPR lab."

Genome Engineering Lab, University of Westminster, UK

Single-tube RNA Extraction

Achieve greater sensitivity, even with low abundance transcripts and small sample volumes

"RNAGEM is a reliable and fast system that only needs a thermocylcer to get good quality RNA from a low number of cells."

TranslaTUM, Munich, Germany

Innovation. Technology. Drive. These are the MicroGEM ingredients to transform the power of molecular biology into point of need solutions for a future of wellness. It’s all captured in our 1-minute video.

This is democratizing molecular biology.

We are simplifying complex molecular techniques, moving them out of highly-skilled labs to non-laboratory settings where they can be used at the point-of-need to solve biological problems.

The first step is rapid nucleic acid extraction, enabling efficient sample preparation with minimal intervention. Whether it’s a farmer’s field in Uganda to diagnose cassava mosaic virus or the depths of the Pacific Ocean to sample and analyze water pathogens, we are putting rapid extraction capabilities in the places they are needed to create the next generation of point-of-need solutions.

The future of point of need.

Optimizing speed, sample size, and simplified workflows

Our enzymatic approach, derived from microorganisms discovered in the extreme environments of the Antarctic and New Zealand, sets the standard for DNA and RNA extraction. Single-tube protocols isolate and stabilize nucleic acids in minutes – not hours – without harsh chemicals or multiple steps. Reduced handling means fewer opportunities for contamination and errors, all saving time and money.

The power of nature.

The versatility of molecular biology.

Find your sample, discover your solution.

Click on your sample type to learn more about our extraction reagents and incorporating them into your workflow.


Nasal-pharyngeal swabs in saline solution, nasal swabs, buccal swabs, and sputum/saliva


Gram-positive, Gram-negative, protozoa, colonies and liquid cultures, biofilm and mucosal, archaea, swabs, and metagenomic DNA (soil, stool, and water)


Plant (leaf, stem, root), plant pathogens, fungi

Cell Culture

Cells in suspension, adhered cells, cell pellets, VACS, and LCM


Sperm cells, semen, semen stains, and vaginal swabs


Mammalian cell culture, laser capture micro-dissections, FACS-prepared cell populations such as macrophages

Liquid blood (fresh, EDTA, heparin, citrate), swab, stains, storage card (FTA)

Animal tissue including insect, mouse and rat tail tips, fish fins, ear tags, fat, muscle, tape lifts, hair

Liquid saliva, swab, stains, storage card (FTA)

MicroGEM’s transformative approach to sample preparation: temperature-driven, enzymatic nucleic acid extraction.

Our single-tube approach removes the need for multiple steps and harsh chemicals needed for conventional extraction methods.

Our thermostable proteinase functions at temperatures perfect for nucleic acid extraction – inactive at low temperatures, turning on at 75°C and irreversibly denaturing at 95°C.

No detergents. No denaturants. No complex steps. Only heat.

That’s temperature-driven nucleic acid extraction done effortlessly.

More about MicroGEM’s approach.

The PDQeX Nucleic Acid Extractor simplifies molecular biology workflows.

MicroGEM’s PDQeX Nucleic Acid Extractor performs temperature-driven extractions on a wide variety of sample types.

MicroGEM offers sophisticated simplicity in the PDQeX Nucleic Acid Extractor – our automated solution for effortless DNA or RNA extraction.  Powerful enzyme-driven reagents and an innovative extraction cartridge produce analytics-ready nucleic acids in less than 15 minutes.

  • Optimized for cell lysis and purification
  • Simplified workflow in a single closed-tube system to handle challenging samples
  • Perfect for labs looking for fast, simple sample processing

More about MicroGEM’s automated solution.

Champagne Pool, Rotorua, New Zealand - an example of an extreme environment that contributes to MicroGEM's one-of-a-kind culture collection.
Champagne Pool, Rotorua, New Zealand

We’ve tapped into the power of extremophiles that thrive in the world’s most extreme conditions.

We use enzymes derived from these microorganisms to quickly and simply extract nucleic acid from many sample types. Temperature-driven enzymatic lysis offers significant advantages.

More about MicroGEM’s one-of-a-kind culture collection.

Dr. David Saul: scientist, explorer, inventor, founder.

Our company is like our culture collection: diverse and strong.

At MicroGEM, we’re explorers and innovators, pushing the boundaries of efficient sample preparation and rapid point-of-need diagnostics.

More about MicroGEM.