Isolating nucleic acids is often the rate-limiting step in molecular diagnostics. Removing inhibitory substances and preparing high-quality extracts with a quick turn-around time are critical for successful downstream processing.
MicroGEM’s PDQeX Nucleic Acid Extractor offers a simple, nearly effortless solution for DNA and RNA extraction for:
Whole Genome Sequencing
MicroGEM’s PDQeX Nucleic Acid Extractor brings together powerful proteinases and mesophilic cell wall degrading enzymes with an innovative extractor cartridge, creating a closed-tube system to lyse cells, destroy nucleases, digest proteins, and release nucleic acids.
This approach prevents contamination and has no laborious sample preparation, while producing extracts in significantly less time (minutes rather than hours) than other extraction methods.
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Latest PDQeX news from our researchers and collaborators
Rapid extraction of DNA suitable for NGS workflows from bacterial cultures using the PDQeX. BioTechniques. 66(5), 2019 (pdf).
This study compared a conventional column purification method with the PDQeX Nucleic Acid Extractor for purifying DNA for whole genome sequencing. Based on six bacterial suspensions, the PDQeX performed much more rapidly – in under 30 minutes – while producing comparable high-quality extractions.
Shaffer, L., Inner Workings: Portable DNA sequencer helps farmers stymie devastating viruses. Proceedings of the National Academy of Sciences. 116(9), 2019 (pdf)
The article describes the ability to screen Cassava crops for Cassava Mosaic Virus (CMV) using MicroGEM’s PDQeX for rapid DNA extraction. The PDQeX was used as the enabling technology to complement DNA sequencing being conducted in the field in real-time.