“Democratizing Molecular Biology: Doing Nucleic Acid Extractions Outside of the Lab.” Labiotech, https://www.labiotech.eu/sponsored/nucleic-acid-extractions-outside-lab/, 25 Sep. 2019. 

“‘Any research that involves a living thing ‒ be it a plant, a person, a microbe ‒ begins with the genome,' says Jeff Chapman, CEO of biotech company MicroGEM. ‘Everything starts with DNA, transcribed into RNA, and then translated into proteins. If you think about it, most life science research has a nucleic acid component to it.'

September 26, 2019 – MicroGEM's nucleic acid extraction technology uses a temperature-driven enzymatic approach to avoid many of the challenges of traditional nucleic acid extraction methods. Conventional methods can take hours to complete, use harsh chemicals and require multiple purification steps. The company’s ultimate goal is to create technologies that can be used by anyone in- and outside of the laboratory.

MicroGEM’s approach uses a single tube, which cuts the overall process time, lowers costs, and reduces the risk of contamination, an issue that many researchers struggle with when using the multiple steps of traditional extraction methods. The single tube can also be used in a standard thermocycler. Moreover, MicroGEM’s nucleic acid extraction method reduces the potential for sample loss, which can occur during conventional extraction processes, enabling the use of very small sample sizes.

While sample preparation had to traditionally be done in a laboratory because of the need for complex tools, MicroGEM’s vision is to enable sample preparation and nucleic acid extraction out of the lab. For this reason, the company developed a portable device called the  PDQeX Nucleic Acid Extractor, which can be integrated into an existing lab’s workflow or outside the laboratory.

MicroGEM is democratizing molecular biology by developing devices that will allow anyone, whether researcher or layperson, to tackle complex biological problems such as measuring gene expression, detecting specific viruses, or authenticating food attributes or components.”

Check out the full Labiotech article here.