April 1, 2019 – Genetic Engineering & Biotechnology News (GEN) today published a corporate profile featuring MicroGEM's temperature-controlled approach to nucleic acid extractions. By leveraging enzymes isolated from extremophiles and mesophiles that turn on and off at specific temperatures, DNA and RNA are easily extracted from a wide range of sample types – including tissue, bacteria, insects, sperm and plant stems, leaves, seeds and roots.
MicroGEM's hands-free, single tube approach is compatible with existing laboratory equipment and provides significant benefits over traditional methods:
- Extremely fast extraction: 5–15 minutes, not hours
- Unprecedented nucleic acid recovery
- Simplified, unattended operation
- Reduced potential for contamination
- High-quality, unbiased DNA/RNA.
Ideal for working with transfected cells, single cells, FACS cells and most laboratory workflows, the DNA and RNA extracts are suitable for STR, PCR, qPCR, RT-PCR and whole genome sequencing. MicroGEM's suite of extraction kits includes prepGEM, the proprietary enzyme used extensively for DNA extraction in CRISPR workflows and for the extraction of nucleic acids from single cells for library preparation in Next-Gen Sequencing.
Also featured is MicroGEM's PDQeX Nucleic Acid Extractor, offering simplified automation over other commercial extraction methods. It uses an innovative extractor cartridge made from thermoresponsive polymers that facilitate extraction and remove enzyme inhibitors through its purification matrix.